Immunomodulators in tick saliva and their benefits
نویسندگان
چکیده
منابع مشابه
Immunomodulators in tick saliva and their benefits.
Ticks are significant bloodsucking ectoparasites. Apart from causing blood loss and host skin damage, ticks are important vectors of tick-borne pathogens that cause disease in humans and animals as well as significant economic loss. For biological success, ticks evolved these substances with immunomodulatory activities capable of inhibiting host defence reactions (haemostasis, inflammation and ...
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Ticks are obligatory blood-sucking ectoparasites and while feeding for a single blood-meal, ticks remain attached to hosts by firmly embedding their barbed mouthparts for several days. Like mosquitoes, they cannot canulate an individual blood vessel; rather, they cause extensive damage in vascular beds and underlying tissues leading to the development of a blood pool, a feeding lesion of ticks....
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When attempting to feed on their hosts, ticks face the problem of host hemostasis (the vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or pain and thus initiate defensive behavior on their hosts) and adaptive immunity (by way of both cellular and humoral responses). Against these barriers, ticks evolved a complex and sophisticated pharmacological armamenta...
متن کاملin translation: translators on their work and what it means
کتاب در باب ترجمه، اثر استر آلن و سوزان برنوفسکی منتشر شده در ماه می 2013 توسط نشریه کلمبیا است. نویسندگان در این کتاب به بررسی 18 مترجم با در نظر گرفتن نقش آثاری که این مترجمان ترجمه کرده اند میپردازند. کتاب به دو بخش تقسیم میشود: " مترجم در جهان" و " کار مترجم" این دو بخش مقالات همیشگی ترجمه و موقعیت خاص ادبیات بیگانه در جهان وسیع امروزی را مورد خطاب قرار میدهد. در این کتاب مقالات متعددی از ن...
Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction
The publication of the first tick sialome (salivary gland transcriptome) heralded a new era of research of tick protease inhibitors, which represent important constituents of the proteins secreted via tick saliva into the host. Three major groups of protease inhibitors are secreted into saliva: Kunitz inhibitors, serpins, and cystatins. Kunitz inhibitors are anti-hemostatic agents and tens of p...
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ژورنال
عنوان ژورنال: Acta virologica
سال: 2013
ISSN: 1336-2305
DOI: 10.4149/av_2013_02_200